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About AMT - Advanced Microscopy Techniques

AMT Building Advanced Microscopy Techniques (AMT) has devoted its design and manufacturing efforts toward the goal of providing excellence in digital camera imaging systems for the TEM.

These systems are sold directly to customers, through domestic and international representatives, and through TEM vendors. With an installed based of over 1100 camera systems, AMT has developed a substantial local and international infrastructure in optics, electronics, software, sales and support. Our use of the best available technologists working together provide excellent customer communication and knowledge. This team approach allows AMT to supply world-class products on a global scale at competitive prices. As a result, AMT enjoys an excellent reputation for reliability and support for both its products and its customers.


Advanced Microscopy Techniques, Corp. (AMT)

242 West Cummings Park, Woburn, MA 01801      Map / Directions

Phone: 978-774-5550     Fax: 978-739-4313     Email: info@amtimaging.com


The Founders

Advanced Microscopy Techniques (AMT) was begun in 1991 as a sole proprietorship by James Mancuso, Ph.D.

Mancuso's career began at Westinghouse's R&D Center and Combustion Engineering where he worked in materials characterization and developed image processing algorithms for semi-conductor inspection and quantitative materials analysis.

Later at ElectroScan he patented the first environmental secondary electron detector and designed ElectroScan's prototype ESEM.

Then at JEOL USA he developed electron optics, electron and ion detectors, SEM metrology systems and motion control modules.

AMT's initial product was adapted from Lee Peachy's (U of Penn) concept of using high-speed machine-vision CCDs at the TEM's "35 mm port". Taking this concept to reality, AMT build the first high-definition, wide-angle camera system in 1991.

Dr. Charlie Bradley

Dr. Charlie Bradley

Email: cbradley@amtimaging.com

In 1992 Leo Fama, who had extensive experience in electro-mechanical design and packaging of semi-conductor equipment and scientific instrumentation, joined AMT as a partner.

Fama expanded the application of fast CCD cameras to virtually all existing TEMs. At the same time, he spearheaded the application of Deben UK's stage control products to semiconductor inspection in SEMs.

He has also headed the sales and support of other Deben products for specimen cooling and SEM beam blanking.

In 1995, experienced TEM microscopist, Charles Bradley, Ph.D. joined to head application software and round out the development team.

Bradley is a physicist who has held positions at Argonne National Laboratory in TEM and 4Pi as an applications software specialist. He has been instrumental in integrating AMT cameras with TEM control systems and extending the application of CCD cameras.

His goal is for the software to be a streamlined acquisition engine that is as efficient as possible, while also recognizing that image processing and acquisition are separate operations.

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AMT's Staff


Adam Manganiello

Adam Manganiello (above)

Joined AMT: 2014

Title: Technical Sales Specialist
Duties Include:
Quotes, Product Demonstrations, and OEM relations

Email: adam@amtimaging.com


Leo Fama Jr.

Leo Fama Jr. (above)

Joined AMT: 2009

Title: Technical Manager
Duties Include:
Mechanical Drawing, Customer Relations, and Component Procurement








Alex Mancuso (above)

Joined AMT:2015

Title: Production Support
Duties Include: Mechanics Assembly, Lens Alignment, and Computer Assembly




Patricia Mancuso (above)

19 years at AMT

Duties include:
Administration, Accounts Payable, Accounts Receivable, Payroll and Insurance, and Show Coordination

Email: pmancuso@amtimaging.com


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Company Milestones

1995: was a big year for AMT, as there were many important developments for the company.

  • AMT incorporated and moved to its previous site in Danvers, Massachusetts.
  • AMT had received several federally funded small business grants (SBIRs) for EBSP detector and SEM measurement systems.
  • AMT had developed both proprietary and patented phosphor technology.
  • AMT introduced its first custom designed finite-conjugate lens for use in TEM cameras. This lens was the basis of the first low cost/high performance 4 megapixel camera available to clinicians.

1998: AMT developed its second finite-conjugate lens, the highly regarded A-lens, for the Advantage HR camera for TEM, which resulted in 3 times higher sensitivity, 2 times faster response, and also had significantly better image quality than previous models.

2000: AMT introduced the Advantage Plus, the first 4 megapixel Side-Mounted TEM camera, again combining progressive scan CCDs with finite-conjugate optics. This was closely followed by the XR60 Side-Mounted camera featuring over 6 megapixels.

2001: AMT developed the C-lens and XR100 TEM camera, which was a 7 megapixel "biological bottom mounted camera" with a very large image pick-up.

2005: AMT’s XR60 was extended to 10.5 megapixels.

2006: AMT adopted Kodak's line of 35 mm format CCDs, which have the best price/pixel ratio available. AMT also introduced the Zoom concept for TEM cameras, whereby the digital camera could be position optimally near the TEM's traditional plate film plane.

2007: AMT introduced its 16000 series, (current XR16), of high speed 16 megapixel TEM cameras. In addition AMT entered an ISV partnership with MicroSoft to integrate database capabilities directly into the camera acquisition software.

2008: AMT introduced 2Vu™. It's method and apparatus allow simultaneous direct viewing and electronic capture of images in a transmission electron microscope (TEM).

2011: 2Vu™ has obtained the patent.

Introduction of the XR50 (5 megapixel), XR80 (8 megapixel) CCD cameras, as well as the XR280 (2.8 megapixel) and the XR550 (5 megapixel) sCMOS camera for transmission electron microscopy (TEM).

AMT Capture Engine Software version 602 became compatible on both XP and Windows 7.

2012: Introduction of two Peltier cooled series, XR81 (8 megapixel) CCD cameras and the XR401 (4 megapixel) sCMOS cameras, for transmission electron microscopy (TEM).

2015: Introduction of new product line, BioSprint (16 megapixel) and the BioSprint12 (12 megapixel) CCD cameras, for transmission electron microscopy (TEM).

2017: Introduction of new product, BioSprint29 (29 megapixel) and the NanoSprint500 sCMOS (5 megapixel) CCD cameras, for transmission electron microscopy (TEM).


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Advanced Microscopy Techniques, Corp. (AMT)

242 West Cummings Park, Woburn, MA 01801     Phone: 978-774-5550     Fax: 978-739-4313     Email: info@amtimaging.com     Map / Directions

Advanced Microscopy Techniques (AMT) manufactures and distributes
high resolution and low dose CCD and sCMOS digital camera systems for Transmission Electron Microscopy (TEM).
Applications in all aspects of life and materials sciences utilize our product line, which include cameras ranging from 43 to 4 megapixels,
NanoSprint43, NanoSprint43-MarkII, NanoSprint12, NanoSprint5, BioSprint29, BioSprint16, BioSprint12, XR81, XR80, and XR401.
Each camera features AMT's original high-resolution, finite-conjugate lenses, creating an extremely flat focus.
AMT sells the digital imaging cameras for TEM directly to customers, through domestic and international representatives, and through TEM vendors.
Established in 1991, AMT is proud to have an installed base of over 2000 units of the TEM camera systems.

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